Article
Effect of periodontal therapy on the course of cyclosporin-induced gingival overgrowth: role of ABCB1 and PAI-1 gene polymorphisms.
Quintessence international (Berlin, Germany : 1985) - 1 Mar 2013
De Iudicibus Sara, Stocco Gabriele, Castronovo Gaetano, Pico Camillo, Racano Roberto, Borelli Massimo, Bevilacqua Lorenzo, Di Lenarda Roberto, Bartoli Fiora, Decorti Giuliana
Abstract excerpt
OBJECTIVES: Etiological periodontal therapy is effective in reducing cyclosporin A-induced gingival overgrowth, but a high variability among subjects has been observed. This study aimed to evaluate the role of polymorphisms in PAI-1 and A BCB1 genes on the course of this side effect following periodontal therapy. METHOD AND MATERIALS: Forty-five transplant patients were subjected to nonsurgical periodontal...
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