Article
Profile of alisporivir and its potential in the treatment of hepatitis C.
Drug design, development and therapy - 1 Jan 2013
Gallay Philippe A, Lin Kai
Abstract excerpt
Two classes of hepatitis C antiviral agents currently exist, i.e., direct-acting antivirals and host-targeting antivirals. Direct-acting antivirals target viral proteins including NS3/NS4A protease, NS5B polymerase and NS5A protein, while host-targeting antivirals target various host proteins critical for replication of the hepatitis C virus (HCV). Alisporivir is the most advanced host-targeting antiviral in...
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