Article
Breast cancer susceptibility associated with rs1219648 (fibroblast growth factor receptor 2) and postmenopausal hormone therapy use in a population-based United States study.
Menopause (New York, N.Y.) - 1 Mar 2013
Andersen Shaneda Warren, Trentham-Dietz Amy, Figueroa Jonine D, Titus Linda J, Cai Qiuyin, Long Jirong, Hampton John M, Egan Kathleen M, Newcomb Polly A
Abstract excerpt
OBJECTIVE: Genomewide association studies have consistently found variants in fibroblast growth factor receptor 2 (FGFR2) to be associated with breast cancer. Recent reports suggest that postmenopausal hormone therapy (HT) use may modify the association between single nucleotide polymorphisms (SNPs) in FGFR2 and breast cancer risk. We assessed the hypothesis that the association between rs1219648 (FGFR2) SNP and...
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