Article
Insomnia with objective short sleep duration: the most biologically severe phenotype of the disorder.
Sleep medicine reviews - 1 Aug 2013
Vgontzas Alexandros N, Fernandez-Mendoza Julio, Liao Duanping, Bixler Edward O
Abstract excerpt
Until recently, the association of chronic insomnia with significant medical morbidity was not established and its diagnosis was based solely on subjective complaints. We present evidence that insomnia with objective short sleep duration is the most biologically severe phenotype of the disorder, as it is associated with cognitive-emotional and cortical arousal, activation of both limbs of the stress system, and a...
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