Article
Evolutionary characterization of the pandemic H1N1/2009 influenza virus in humans based on non-structural genes.
PloS one - 1 Jan 2013
Wang Chengmin, Zhang Yanyu, Wu Bin, Liu Shelan, Xu Ping, Lu Yanmin, Luo Jing, Nolte Dale Louis, Deliberto Thomas Jude, Duan Mingxing, Zhang Hong, He Hongxuan
Abstract excerpt
The 2009 influenza pandemic had a tremendous social and economic impact. To study the genetic diversity and evolution of the 2009 H1N1 virus, a mutation network for the non-structural (NS) gene of the virus was constructed. Strains of the 2009 H1N1 pandemic influenza A virus could be divided into two categories based on the V123I mutation in the NS1 gene: G1 (characterized as 123 Val) and G2 (characterized as 123...
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