Article
Lipoprotein abnormalities in compound heterozygous lipoprotein lipase deficiency after treatment with a low-fat diet and orlistat.
Journal of clinical lipidology - 1 Jan 2000
Blackett Piers, Tryggestad Jeanie, Krishnan Sowmya, Li Shibo, Xu Weihong, Alaupovic Petar, Quiroga Carmen, Copeland Kenneth
Abstract excerpt
BACKGROUND: The treatment of familial hyperchylomicronemia presenting in early childhood with episodes of pancreatitis has been ineffective, and affected patients remain at risk for pancreatitis. OBJECTIVE: To report on the effect of orlistat in siblings with severe inherited hyperchylomicronemia and to assess posttreatment lipoprotein concentrations and composition. METHODS: Serial observations of plasma lipid...
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