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Article

Functional domain for priming activity in the phage phi 29 terminal protein.

Gene - 30 Mar 1990

Garmendia C, Hermoso J M, Salas M

Abstract excerpt

By site-directed mutagenesis we have changed into Cys the Ser232 of the phi 29 terminal protein (TP) involved in the covalent linkage to dAMP for the initiation of replication. The mutant TP, highly purified, had about 0.7% of the priming activity of the wild-type (wt) protein p3. The linkage bet...

Topics

Amino Acid Sequence
Bacteriophages
DNA Replication
DNA-Directed DNA Polymerase
Molecular Sequence Data
Mutation
Viral Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2341040
DOI: 10.1016/0378-1119(90)90061-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2341040-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Functional domain for priming activity in the phage phi 29 terminal protein.PMID 2341040Read ↗

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