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Article

Sequence Analysis of Transplacentally Acquired Human Herpesvirus 6 DNA Is Consistent With Transmission of a Chromosomally Integrated Reactivated Virus

13 Feb 2013

Abstract excerpt

The majority of human herpesvirus 6 (HHV-6) congenital infections (86%) originate from germ line transmission of chromosomally integrated HHV-6 (ciHHV-6). To determine whether transplacentally acquired HHV-6 could derive from the transmission of reactivated maternal ciHHV-6, we identified mother-infant pairs in which infants had proven transplacentally acquired HHV-6 and mothers had documented ciHHV-6, and we...

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PMID: 23408849
DOI: 10.1093/infdis/jit060

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