Article
Analysis of circulating populations of Plasmodium falciparum in mild and severe malaria in two different epidemiological patterns in Madagascar.
Tropical medicine & international health : TM & IH - 1 Nov 2008
Durand Rémy, Ariey Frédéric, Cojean Sandrine, Fontanet Arnaud, Ranaivo Louise, Ranarivelo Lanto-Alisoa, Vonimpaisomihanta Jeanne Aimée, Menard Didier, Pietra Virginio, Le Bras Jacques, Modiano David, Randrianarivelojosia Milijaona
Abstract excerpt
OBJECTIVE: To investigate whether the severity of Plasmodium falciparum attack in endemic areas was associated with the multiplicity of infection (MOI) and/or with a particular genotype(s). METHOD: In two areas of different malaria transmission pattern in Madagascar (Sainte-Marie - mesoendemic and Tsiroanomandidy - hypoendemic) the number and the proportions of msp-2 genotypes within isolates were determined for...
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