Article
A novel missense mutation in the NYX gene associated with high myopia.
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) - 1 May 2013
Yip Shea Ping, Li Choi Chu, Yiu Wai Chi, Hung Wing Hong, Lam Wai Wa, Lai Man Chi, Ng Po Wah, Fung Wai Yan, Chu Patrick H W, Jiang Bo, Chan Henry H L, Yap Maurice K H
Abstract excerpt
PURPOSE: Myopia is a complex eye disorder. The X-linked form of complete congenital stationary night blindness (CSNB1A) is usually associated with moderate to high myopia, and is caused by mutations in the NYX gene. We explored if NYX mutations could be associated with high myopia, but not CSNB1A. METHODS: The coding regions of the NYX gene were sequenced for 204 Chinese males with high myopia (-8.00 dioptres or...
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