Article
The sinR ortholog PGN_0088 encodes a transcriptional regulator that inhibits polysaccharide synthesis in Porphyromonas gingivalis ATCC 33277 biofilms.
PloS one - 1 Jan 2013
Yamamoto Reiko, Noiri Yuichiro, Yamaguchi Mikiyo, Asahi Yoko, Maezono Hazuki, Kuboniwa Masae, Hayashi Mikako, Ebisu Shigeyuki
Abstract excerpt
Biofilm-forming cells are distinct from well characterized planktonic cells and aggregate in the extracellular matrix, the so-called extracellular polymeric substances (EPS). The sinR gene of Bacillus subtilis encodes a transcriptional regulator that is known to be involved in the biosynthesis of EPS in biofilms. Porphyromonas gingivalis inhabits the subgingival and extraradicular biofilm of humans and is one of...
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