Article
The contribution of caveolin-1 genotype and phenotype to hepatocellular carcinoma.
Anticancer research - 1 Feb 2013
Hsu Chin-Mu, Yang Mei-Due, Tsai Chia-Wen, Ho Chien-Yi, Chang Wen-Shin, Chang Sheng-Chi, Jeng Long-Bin, Tsai Yuhsin, Tsai Fuu-Jen, Bau Da-Tian
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common types of malignant tumors worldwide, for which the prevalence and mortality rates are very high in Taiwan. Caveolin-1 (CAV-1) is a main structural protein of caveolae and plays a regulatory role in signaling pathways and tumorigenesis. High expression of Cav-1 in mouse HCC is positively correlated with higher cell invasive capacity, but the...
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