Article
TGF-α/HA complex promotes tympanic membrane keratinocyte migration and proliferation via ErbB1 receptor.
Experimental cell research - 1 Apr 2013
Mei Teh Bing, Redmond Sharon L, Shen Yi, Atlas Marcus D, Marano Robert J, Dilley Rodney J
Abstract excerpt
Tympanic membrane perforations are common and represent a management challenge to clinicians. Current treatments for chronic perforations involve a graft surgery and require general anaesthesia, including associated costs and morbidities. Bioactive molecules (e.g. growth factors, cytokines) play an important role in promoting TM wound healing following perforation and the use of growth factors as a topical...
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