Broad spectrum beta-lactamases of Citrobacter diversus.

doi:10.1093/jac/25.3.335

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Article

Broad spectrum beta-lactamases of Citrobacter diversus.

The Journal of antimicrobial chemotherapy - 1 Mar 1990

Oliva B, Segatore B, Amicosante G, Franceschini N, Oratore A, Bennett P M

Abstract excerpt

Citrobacter diversus NF85 produced a chromosomal beta-lactamase that was induced by a variety of beta-lactam antibiotics. Two major forms of the enzyme, with isoelectric points (pI's) of 5.7 and 6.2, were found in crude cell extracts. Derepressed mutants of NF85, generated by nitrosoguanidine tre...

Topics

Anti-Bacterial Agents
Citrobacter
Enzyme Induction
Isoelectric Focusing
Microbial Sensitivity Tests
Mutation
beta-Lactamases
beta-Lactams

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