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Article

Shared dysregulated pathways lead to Parkinson's disease and diabetes.

Trends in molecular medicine - 1 Mar 2013

Santiago Jose A, Potashkin Judith A

Abstract excerpt

Recent evidence indicates that Parkinson's disease and diabetes, both age-related chronic diseases, share remarkably similar dysregulated pathways. Exposure to environmental factors and genetic susceptibility play a role in the etiology and progression of both diseases. In light of recent findings, an intriguing hypothesis has emerged that suggests that mitochondrial dysfunction, endoplasmic reticulum stress,...

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PMID: 23375873
DOI: 10.1016/j.molmed.2013.01.002

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