Article
Maintenance of "stem cell" features of cartilage cell sub-populations during in vitro propagation.
Journal of translational medicine - 30 Jan 2013
Benz Karin, Stippich Claudia, Freudigmann Christian, Mollenhauer Juergen A, Aicher Wilhelm K
Abstract excerpt
BACKGROUND: The discovery of mesenchymal stem cells (MSCs) or MSC-like cells in cartilage tissue does not tie in well with the established view that MSCs derive from a perivascular niche. The presence of MSCs may raise concerns about specificity and application safety, particularly in terms of the regulatory site. The aim of the present study was to investigate the benefits or possible risks of the MSC-like...
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