Article
Comparison and contrast of genes and biological pathways responding to Marek's disease virus infection using allele-specific expression and differential expression in broiler and layer chickens.
BMC genomics - 30 Jan 2013
Perumbakkam Sudeep, Muir William M, Black-Pyrkosz Alexis, Okimoto Ron, Cheng Hans H
Abstract excerpt
BACKGROUND: Marek's disease (MD) is a commercially important neoplastic disease of chickens caused by the Marek's disease virus (MDV), a naturally occurring oncogenic alphaherpesvirus. Enhancing MD genetic resistance is desirable to augment current vaccines and other MD control measures. High throughput sequencing was used to profile splenic transcriptomes from individual F1 progeny infected with MDV at 4 days of...
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