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Transcriptional analysis of host responses to Marek’s disease virus infection in genetically resistant and susceptible chickens

26 Mar 2008

Abstract excerpt

Summary Marek’s disease virus (MDV) is a cell‐associated oncogenic herpesvirus that targets B cells and T cells, inducing lymphoid tumours in chickens. Genetic resistance to Marek’s disease (MD) is regulated in a polygenic fashion. In this study, we sought to compare the gene expression profiles following infection of birds that are genetically resistant or susceptible to MD (with the B21 and B19 haplotypes...

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PMID: 18371127
DOI: 10.1111/j.1365-2052.2008.01710.x

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