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Article

High and low dose responses of transcriptional biomarkers in <i>ex vivo</i> X-irradiated human blood

30 Jan 2013

Abstract excerpt

PURPOSE: Modifications of gene expression following ionizing radiation (IR) exposure of cells in vitro and in vivo are well documented. However, little is known about the dose-responses of transcriptionally responsive genes, especially at low doses. In this study, we investigated these dose-responses and assessed inter-individual variability. MATERIALS AND METHODS: High dose (0.5-4 Gy) and low dose (5-100 mGy)...

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PMID: 23362884
DOI: 10.3109/09553002.2013.769694

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