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Article

Conditional and domain-specific inactivation of the Tsc2 gene in neural progenitor cells.

Genesis (New York, N.Y. : 2000) - 1 Apr 2013

Fu Cary, Ess Kevin C

Abstract excerpt

Tuberous sclerosis complex (TSC) is a genetic disease characterized by multiorgan benign tumors as well as neurological manifestations. Epilepsy and autism are two of the more prevalent neurological complications and are usually severe. TSC is caused by mutations in either the TSC1 (encodes hamartin) or the TSC2 (encodes tuberin) genes with TSC2 mutations being associated with worse outcomes. Tuberin contains a...

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Share to Founder Effect
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23359422
DOI: 10.1002/dvg.22377
PMCID: PMC3633697

Genes

TSC2
TSC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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