Article
The ratio of insulin-like growth factor-I/insulin-like growth factor-binding protein-3 in sera of patients with hepatitis C virus-related chronic liver disease as a predictive marker of insulin resistance.
Nutrition research (New York, N.Y.) - 1 Jan 2013
Himoto Takashi, Tani Joji, Miyoshi Hisaaki, Yoneyama Hirohito, Mori Hirohito, Inukai Michio, Masugata Hisashi, Goda Fuminori, Senda Shoichi, Haba Reiji, Masaki Tsutomu
Abstract excerpt
Recent studies have elucidated a lower level of serum insulin-like growth factor-I (IGF-I) or a decrease in the IGF-I/IGF-binding protein-3 (IGFBP-3) ratio in patients with type 2 diabetes mellitus or hepatic steatosis. Persistent hepatitis C virus (HCV) infection often evokes metabolic abnormalities including hepatic steatosis and insulin resistance. We hypothesized that the relationship between the ratio of...
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