Integrating genetic and imaging investigations into the clinical management of congenital hyperinsulinism

Abstract excerpt

Congenital Hyperinsulinism (CHI) is a rare but important cause of hypoglycaemia in infancy. CHI is a heterogeneous disease, but has a strong genetic basis; a number of genetic causes have been identified with CHI in about a third of individuals, chiefly in the genes that code for the ATP sensitive K(+) channels (KATP ) in the pancreatic β-cells. Rapid KATP channel gene testing is a critical early step in the...

Topics

Join the communities discussing this publication.

• Hyperglycemia and glycemic control in critically ill and hospitalized patients
• Medical Imaging Techniques and Applications
• Pancreatic and Hepatic Oncology Research