Recurrent severe oligohydramnios and fetal pulmonary hypoplasia associated with ErbB4 mutation.

Abstract excerpt

BACKGROUND: Pulmonary hypoplasia resulting from oligohydramnios or anhydramnios can cause severe respiratory compromise in newborn patients. We report a case of recurrent oligohydramnios in a mother with an ErbB4 mutation and speculate that the effects on the placenta through decreased vascularization contributed to oligohdyramnios and subsequent pulmonary hypoplasia in the newborn. CASE: The pregnant mother in...

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