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Differentiation of mouse induced pluripotent stem cells into corneal epithelial‐like cells

4 Dec 2012

Abstract excerpt

Somatic cells can be reprogrammed into a pluripotent ES-cell-like state (termed induced pluripotent stem cells, iPS) by transcription factors, which have enormous therapeutic potential for regenerative medicine. We have investigated whether iPS can directly differentiate into corneal epithelium-like cells. Mouse iPS cells were co-cultured with corneal limbal stroma. RT-PCR, immunohistochemistry and scanning...

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PMID: 23339091
DOI: 10.1002/cbin.10007

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