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Article

RNAsnp: efficient detection of local RNA secondary structure changes induced by SNPs.

Human mutation - 1 Apr 2013

Sabarinathan Radhakrishnan, Tafer Hakim, Seemann Stefan E, Hofacker Ivo L, Stadler Peter F, Gorodkin Jan

Abstract excerpt

Structural characteristics are essential for the functioning of many noncoding RNAs and cis-regulatory elements of mRNAs. SNPs may disrupt these structures, interfere with their molecular function, and hence cause a phenotypic effect. RNA folding algorithms can provide detailed insights into stru...

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PMID: 23315997
DOI: 10.1002/humu.22273
PMCID: PMC3708107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23315997-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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