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Fetal programming of CVD and renal disease: animal models and mechanistic considerations

14 Jan 2013

Abstract excerpt

The developmental origins of health and disease hypothesis postulates that exposure to a less than optimal maternal environment during fetal development programmes physiological function, and determines risk of disease in adult life. Much evidence of such programming comes from retrospective epidemiological cohorts, which demonstrate associations between birth anthropometry and non-communicable diseases of...

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PMID: 23312451
DOI: 10.1017/s0029665112003035

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