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Article

Profiling sirolimus-induced inflammatory syndrome: a prospective tricentric observational study.

PloS one - 1 Jan 2013

Buron Fanny, Malvezzi Paolo, Villar Emmanuel, Chauvet Cécile, Janbon Bénédicte, Denis Laure, Brunet Maria, Daoud Sameh, Cahen Rémi, Pouteil-Noble Claire, Gagnieu Marie-Claude, Bienvenu Jacques, Bayle François, Morelon Emmanuel, Thaunat Olivier

Abstract excerpt

BACKGROUND: The use of the immunosuppressant sirolimus in kidney transplantation has been made problematic by the frequent occurrence of various side effects, including paradoxical inflammatory manifestations, the pathophysiology of which has remained elusive. METHODS: 30 kidney transplant recipients that required a switch from calcineurin inhibitor to sirolimus-based immunosuppression, were prospectively...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23308138
DOI: 10.1371/journal.pone.0053078
PMCID: PMC3538748

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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