Article
Analysis of naturally occurring deletion variants of African swine fever virus: multigene family 110 is not essential for infectivity or virulence in pigs.
Virology - 1 May 1990
Agüero M, Blasco R, Wilkinson P, Viñuela E
Abstract excerpt
A comparison of uncloned African swine fever virus isolates with their cloned counterparts revealed the presence of genetic variants in three out of seven uncloned field virus populations tested. Five different virus clones were isolated from the uncloned KIR69 virus stock by limit dilution. Structural analysis of the variants showed that they differed by single deletions of 10-16 kilobases in the region located...
Topics
- African Swine Fever
- African Swine Fever Virus
- Animals
- Base Sequence
- Cells, Cultured
- DNA, Viral
- Iridoviridae
- Macrophages
- Molecular Sequence Data
- Multigene Family
- Mutation
