Article
Bone marrow transplantation from a pediatric donor with a high frequency of cytomegalovirus-specific T-cells.
Journal of medical virology - 1 Dec 2006
Komatsu Haruki, Kogawa Kazuhiro, Nonoyama Shigeaki, Inui Ayno, Sogo Tsuyoshi, Fujisawa Tomoo, Klenerman Paul
Abstract excerpt
A recent study reported that quantitation of cytomegalovirus (CMV)-specific CD8+ T lymphocytes in the graft and monitoring of these T cells might identify hematopoietic stem cell transplantation-recipients at the risk for progressive CMV infection. A 6-year-old girl underwent bone marrow transplantation from an HLA-identical sibling with a very high frequency of CMV specific tetramer-positive CD8+ T-cells....
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