Article
Earle's balanced salts solution and rapamycin differentially regulate the Bacillus Calmette-Guerin-induced maturation of human dendritic cells.
Acta biochimica et biophysica Sinica - 1 Mar 2013
Min Yan, Xu Wenxi, Liu Dan, Shen Hongbo, Xu Ying, Zhang Shulin, Zhang Lu, Wang Honghai
Abstract excerpt
Autophagy has been shown to enhance the efficacy of the Bacillus Calmette-Guérin (BCG) vaccine by increasing the peptide presentation of dendritic cells (DCs). Earle's balanced salts solution (EBSS) is a saline solution with physiological pH which is often used to induce autophagy, while rapamycin is a pharmacological reagent used for autophagy induction. In the present study, we studied the effect of EBSS and...
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