Article
Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes.
Carcinogenesis - 1 Apr 2013
Shi Ting-Yan, Cheng Xi, Yu Ke-Da, Sun Meng-Hong, Shao Zhi-Ming, Wang Meng-Yun, Zhu Mei-Ling, He Jing, Li Qiao-Xin, Chen Xiao-Jun, Zhou Xiao-Yan, Wu Xiaohua, Wei Qingyi
Abstract excerpt
Tumor necrosis factor-α-induced protein 8 (TNFAIP8) is an anti apoptotic and pro-oncogenic signaling molecule involved in the process of immunity, carcinogenesis and tumor progression. Single nucleotide polymorphisms (SNPs) at microRNA-binding sites may change messenger RNA target gene function, thus leading to cancer susceptibility and tumor progression. In this study of 1584 cervical cancer cases and 1394...
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