Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes.

doi:10.1093/carcin/bgt001

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Article

Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes.

Carcinogenesis - 1 Apr 2013

Shi Ting-Yan, Cheng Xi, Yu Ke-Da, Sun Meng-Hong, Shao Zhi-Ming, Wang Meng-Yun, Zhu Mei-Ling, He Jing, Li Qiao-Xin, Chen Xiao-Jun, Zhou Xiao-Yan, Wu Xiaohua, Wei Qingyi

Abstract excerpt

Tumor necrosis factor-α-induced protein 8 (TNFAIP8) is an anti apoptotic and pro-oncogenic signaling molecule involved in the process of immunity, carcinogenesis and tumor progression. Single nucleotide polymorphisms (SNPs) at microRNA-binding sites may change messenger RNA target gene function, thus leading to cancer susceptibility and tumor progression. In this study of 1584 cervical cancer cases and 1394...

Topics

3' Untranslated Regions
Apoptosis Regulatory Proteins
Case-Control Studies
Cell Line, Tumor
China
Cisplatin
Drug Resistance, Neoplasm
Female
Genetic Association Studies
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

MicroRNAs

Organoplatinum Compounds

Paclitaxel

Polymorphism, Single Nucleotide

Risk

Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 23299407
DOI: 10.1093/carcin/bgt001

Genes

TNFAIP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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