Article
Dacomitinib, a new therapy for the treatment of non-small cell lung cancer.
Expert opinion on pharmacotherapy - 1 Feb 2013
Brzezniak Christina, Carter Corey A, Giaccone Giuseppe
Abstract excerpt
INTRODUCTION: Advanced or metastatic non-small cell lung cancer (NSCLC) is characterized by a poor prognosis and few second- or third-line treatments. First-generation reversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibition (TKI) has paved the way for targeted treatment in lung cancer. These drugs result in excellent responses in patients with activating EGFR mutations. Unfortunately,...
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