Article
A comprehensive SNP and indel imputability database.
Bioinformatics (Oxford, England) - 15 Feb 2013
Duan Qing, Liu Eric Yi, Croteau-Chonka Damien C, Mohlke Karen L, Li Yun
Abstract excerpt
MOTIVATION: Genotype imputation has become an indispensible step in genome-wide association studies (GWAS). Imputation accuracy, directly influencing downstream analysis, has shown to be improved using re-sequencing-based reference panels; however, this comes at the cost of high computational burden due to the huge number of potentially imputable markers (tens of millions) discovered through sequencing a large...
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