[Adrenogenital syndrome. II. Molecular biology].

Article

[Adrenogenital syndrome. II. Molecular biology].

Tijdschrift voor kindergeneeskunde - 1 Feb 1991

Koppens P F, Hoogenboezem T, Degenhart H J

Abstract excerpt

The adrenogenital syndrome (AGS) is usually caused by steroid 21-hydroxylase deficiency. Two steroid 21-hydroxylase genes are present within the major histocompatibility complex (MHC) on chromosome 6: an active gene (CYP21) and a pseudogene (CYP21P). Several types of mutations have been described...

Topics

Adrenal Hyperplasia, Congenital
Chromosome Deletion
Chromosomes, Human, Pair 6
DNA Probes
Genes, MHC Class I
Humans
Major Histocompatibility Complex
Mutation
Polymorphism, Restriction Fragment Length
Steroid 21-Hydroxylase

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.