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Article

A Pathway-Based Analysis on the Effects of Obstructive Sleep Apnea in Modulating Visceral Fat Transcriptome

31 Dec 2012

Abstract excerpt

RATIONALE: Obstructive sleep apnea (OSA) has been associated with metabolic dysregulation and systemic inflammation. This may be due to pathophysiologic effects of OSA on visceral adipose tissue. We sought to assess the transcriptional consequences of OSA on adipocytes by utilizing pathway-focused analyses. METHODS: Patients scheduled to undergo ventral hernia repair surgery were recruited to wear a portable home...

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PMID: 23288968
DOI: 10.5665/sleep.2294

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