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Article

Developmental analysis and influence of genetic background on the Lhx3 W227ter mouse model of combined pituitary hormone deficiency disease.

Endocrinology - 1 Feb 2013

Prince Kelly L, Colvin Stephanie C, Park Soyoung, Lai Xianyin, Witzmann Frank A, Rhodes Simon J

Abstract excerpt

Combined pituitary hormone deficiency (CPHD) diseases result in severe outcomes for patients including short stature, developmental delays, and reproductive deficiencies. Little is known about their etiology, especially the developmental profiles and the influences of genetic background on disease progression. Animal models for CPHD provide valuable tools to investigate disease mechanisms and inform diagnostic...

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Identifiers

PMID: 23288907
DOI: 10.1210/en.2012-1790
PMCID: PMC3548188

Genes

PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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