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Article

A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus

1 Jan 2012

Abstract excerpt

Most cells of the developing mammalian brain derive from the ventricular (VZ) and the subventricular (SVZ) zones. The VZ is formed by the multipotent radial glia/neural stem cells (NSCs) while the SVZ harbors the rapidly proliferative neural precursor cells (NPCs). Evidence from human and animal models indicates that the common history of hydrocephalus and brain maldevelopment starts early in embryonic life with...

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Share to Cerebrospinal fluid and hydrocephalus
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PMID: 23283433
DOI: 10.4067/s0716-97602012000300005

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