Essential thrombocythemia in two sisters originating from different stem cell levels.

Article

Essential thrombocythemia in two sisters originating from different stem cell levels.

Blood - 15 Apr 1990

Janssen J W, Anger B R, Drexler H G, Bartram C R, Heimpel H

Abstract excerpt

We report the rare occurrence of essential thrombocythemia (ET) in two sisters. In one patient, the clinical phenotype of the disease evolved from ET to polycythemia vera (PV) after 4 years of follow-up. Clonal hematopoiesis was established in both cases by X-chromosomal inactivation analysis usi...

Topics

Aged
Cell Separation
Family Health
Female
Hematopoietic Stem Cells
Humans
Myeloproliferative Disorders
Phenotype
Thrombocythemia, Essential

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