Article
Screening of SLC26A4 gene in autoimmune thyroid diseases.
International journal of immunogenetics - 1 Aug 2013
Kallel R, Niasme-Grare M, Belguith-Maalej S, Mnif M, Abid M, Ayadi H, Masmoudi S, Jonard L, Hadj Kacem H
Abstract excerpt
The Pendred syndrome (PS) gene, SLC26A4, was involved in the genetic susceptibility of autoimmune thyroid disease (AITD) in Tunisian population. Recently, functional assays have shown a differential expression of SLC26A4 gene between Graves' disease (GD) and Hashimoto's thyroiditis (HT). Here, by the mean of DHPLC and HRM, we explored the 21 exons and their flanking intronic sequences of 128 patients affected...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.