Article
[Telaprevir: new possibilities for antiviral treatment in patients with chronic hepatitis C].
Terapevticheskii arkhiv - 1 Jan 2012
Nikitin I G, Gogova L M, Baikova I E, Kislyakov V A, Volynkina V M
Abstract excerpt
The review considers the chemical structure, pharmacodynamics and pharmacokinetics of telaprevir, a new direct-acting antiviral agent, used to treat patients with chronic hepatitis C (CHC). The given data on Phase II and III clinical trials enable the authors to state the high efficacy of the drug in patients infected with hepatitis C virus type 1. The paper also provides data on the resistance of telaprevir and...
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