Article
Protective Roles of Grass Carp Ctenopharyngodon idella Mx Isoforms against Grass Carp Reovirus
14 Dec 2012
Abstract excerpt
BACKGROUND: Myxovirus resistance (Mx) proteins are crucial effectors of the innate antiviral response against a wide range of viruses, mediated by the type I interferon (IFN-I) signaling pathway. However, the antiviral activity of Mx proteins is diverse and complicated in different species. METHODOLOGY/PRINCIPAL FINDINGS: In the current study, two novel Mx genes (CiMx1 and CiMx3) were identified in grass carp...
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