The HIF1A gene Pro582Ser polymorphism in Russian strength athletes.

doi:10.1519/JSC.0b013e31827f06ae

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Article

The HIF1A gene Pro582Ser polymorphism in Russian strength athletes.

Journal of strength and conditioning research - 1 Aug 2013

Gabbasov Rashid T, Arkhipova Alina A, Borisova Alyona V, Hakimullina Albina M, Kuznetsova Alexandra V, Williams Alun G, Day Stephen H, Ahmetov Ildus I

Abstract excerpt

Hypoxia-inducible factor-1α (encoded by HIF1A gene) controls a number of genes that are implicated in various cellular functions including glycolysis and cell proliferation and differentiation. The rs11549465 C > T polymorphism in the HIF1A gene, which produces the amino acid substitution Pro582Ser, increases protein stability and transcriptional activity and, therefore, improves glucose metabolism. The aim of...

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PMID: 23222085
DOI: 10.1519/JSC.0b013e31827f06ae

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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