Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA 146 (Mir146) Modulates Spermatogonial Differentiation by Retinoic Acid in Mice1

6 Dec 2012

Abstract excerpt

Impaired biogenesis of microRNAs disrupts spermatogenesis and leads to infertility in male mice. Spermatogonial differentiation is a key step in spermatogenesis, yet the mechanisms that control this event remain poorly defined. In this study, we discovered microRNA 146 (Mir146) to be highly regulated during spermatogonial differentiation, a process dependent on retinoic acid (RA) signaling. Mir146 transcript...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to MicroRNA in disease regulation
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23221399
DOI: 10.1095/biolreprod.112.103747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA 146 (Mir146) Modulates Spermatogonial Differentiation by Retinoic Acid in Mice1PMID 23221399Read ↗

MicroRNA signature in various cell types of mouse spermatogenesis: Evidence for stage‐specifically expressed miRNA‐221, ‐203 and ‐34b‐5p mediated spermatogenesis regulationSemantic proximity Read ↗

The Role of Retinoic Acid (RA) in Spermatogonial Differentiation1Semantic proximity Read ↗

microRNAs in the Testis: Building Up Male FertilitySemantic proximity Read ↗

Roles ofStra8andTcerg1lin retinoic acid induced spermatogonial differentiation in mouseSemantic proximity Read ↗

Expression of Mirlet7 Family MicroRNAs in Response to Retinoic Acid-Induced Spermatogonial Differentiation in Mice1Semantic proximity Read ↗

MicroRNAs 221 and 222 regulate the undifferentiated state in mammalian male germ cellsSemantic proximity Read ↗

Small RNA molecules in the regulation of spermatogenesisSemantic proximity Read ↗

MicroRNA-202 maintains spermatogonial stem cells by inhibiting cell cycle regulators and RNA binding proteinsSemantic proximity Read ↗

Recent Update on Retinoic Acid-Driven Initiation of Spermatogonial DifferentiationSemantic proximity Read ↗

MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and SpermatogenesisSemantic proximity Read ↗

MicroRNA-30a-5p promotes differentiation in neonatal mouse spermatogonial stem cells (SSCs)Semantic proximity Read ↗

miR‐100 promotes the proliferation of spermatogonial stem cells via regulating Stat3Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.