Article
Drift load in populations of small size and low density.
Heredity - 1 Mar 2013
Willi Y, Griffin P, Van Buskirk J
Abstract excerpt
According to theory, drift load in randomly mating populations is determined by past population size, because enhanced genetic drift in small populations causes accumulation and fixation of recessive deleterious mutations of small effect. In contrast, segregating load due to mutations of low frequency should decline in smaller populations, at least when mutations are highly recessive and strongly deleterious....
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