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Article

[MITO-Porter; a cutting-edge technology for mitochondrial gene therapy].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Jan 2012

Furukawa Ryo, Yamada Yuma, Harashima Hideyoshi

Abstract excerpt

Gene therapy is an attractive strategy, for not only targeting nuclear genome, but the mitochondrial genome as well. Human mitochondrial DNA (mtDNA) encodes 13 subunits of the electron transport chain, 22 tRNAs, and 2 rRNAs and their mutations cause a wide range of mitochondrial diseases. Each cell contains hundreds to thousands of mtDNAs, and in the case of a diseased cell, the mitochondrion possesses both...

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PMID: 23208046
DOI: 10.1248/yakushi.12-00235-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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