Article
Primary intraplacental gestational choriocarcinoma: histologic and genetic analyses.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2013
Kanehira Kazunori, Starostik Petr, Kasznica John, Khoury Thaer
Abstract excerpt
Gestational choriocarcinoma is a highly malignant form of gestational trophoblastic tumors. Placental involvement of the tumor is exceedingly rare. We describe a case of intraplacental choriocarcinoma in a full-term placenta. Microscopically, there were sheets of highly pleomorphic trophoblasts invading the placenta, leaving isolated chorionic villi within the tumor. We utilized molecular genetic methods to...
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