Article
Influence of maternal low protein diet during pregnancy on hepatic gene expression signature in juvenile female porcine offspring.
Molecular nutrition & food research - 1 Feb 2013
Döring Frank, Lüersen Kai, Schmelzer Constance, Hennig Steffen, Lang Iris S, Görs Solvig, Rehfeldt Charlotte, Otten Winfried, Metges Cornelia C
Abstract excerpt
SCOPE: Epidemiological and experimental evidence indicates that maternal nutrition status contributes to long-term changes in the metabolic phenotype of the offspring, a process known as fetal programming. METHODS AND RESULTS: We have used a swine model (Sus scrofa) to analyze consequences of a maternal low protein diet (about 50% of control) during pregnancy on hepatic lipid metabolism and genome-wide hepatic...
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