Article
Portable chemiluminescence multiplex biosensor for quantitative detection of three B19 DNA genotypes.
Analytical and bioanalytical chemistry - 1 Jan 2013
Mirasoli Mara, Bonvicini Francesca, Dolci Luisa Stella, Zangheri Martina, Gallinella Giorgio, Roda Aldo
Abstract excerpt
A miniaturized multiplex biosensor exploiting a microfluidic oligonucleotide array and chemiluminescence (CL) lensless imaging detection has been developed for parvovirus B19 genotyping. The portable device consists of a reaction chip, comprising a glass slide arrayed with three B19 genotype-specific probes and coupled with a polydimethylsiloxane microfluidic layer, and a charge-coupled device camera modified for...
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