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Article

RNAi-Mediated Silencing of Paramyosin Expression in Trichinella spiralis Results in Impaired Viability of the Parasite

21 Nov 2012

Abstract excerpt

BACKGROUND: Trichinella spiralis expresses paramyosin (Ts-PMY) not only as a structural protein but also as an immunomodulatory protein to protect the worm from being attacked by host complement components. In this study, the functions of PMY in the viability and the growth development of T. spiralis were confirmed at the first time by silencing the gene function with RNA interference technique. METHODS AND...

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PMID: 23185483
DOI: 10.1371/journal.pone.0049913

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