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Multiple Kisspeptin Receptors in Early Osteichthyans Provide New Insights into the Evolution of This Receptor Family

20 Nov 2012

Abstract excerpt

Deorphanization of GPR54 receptor a decade ago led to the characterization of the kisspeptin receptor (Kissr) in mammals and the discovery of its major role in the brain control of reproduction. While a single gene encodes for Kissr in eutherian mammals including human, other vertebrates present a variable number of Kissr genes, from none in birds, one or two in teleosts, to three in an amphibian, xenopus. In...

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PMID: 23185286
DOI: 10.1371/journal.pone.0048931

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Multiple Kisspeptin Receptors in Early Osteichthyans Provide New Insights into the Evolution of This Receptor FamilyPMID 23185286Read ↗

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